Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic control by a metabolite binding mRNA.

Chemistry & biology - 1 Sept 2002

Nahvi Ali, Sudarsan Narasimhan, Ebert Margaret S, Zou Xiang, Brown Kenneth L, Breaker Ronald R

Abstract excerpt

Messenger RNAs are typically thought of as passive carriers of genetic information that are acted upon by protein- or small RNA-regulatory factors and by ribosomes during the process of translation. We report that the 5'-untranslated sequence of the Escherichia coli btuB mRNA assumes a more proactive role in metabolic monitoring and genetic control. The mRNA serves as a metabolite-sensing genetic switch by...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 5' Untranslated Regions
Share to Allosteric Regulation
Share to Bacterial Outer Membrane Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, Reporter

Share to Membrane Transport Proteins

Share to Nucleic Acid Conformation

Share to Receptors, Peptide

Share to RNA, Bacterial

Source

Identifiers

PMID: 12323379
DOI: 10.1016/s1074-5521(02)00224-7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

Genetic control by a metabolite binding mRNA.PMID 12323379Read ↗

Thiamine derivatives bind messenger RNAs directly to regulate bacterial gene expression.Semantic proximity Read ↗

The RpfB switch is a novel B <sub>12</sub> -sensing riboswitch regulating (non-replicating) persistence in <i>Mycobacterium tuberculosis</i>Semantic proximity Read ↗

Riboswitches control fundamental biochemical pathways in Bacillus subtilis and other bacteria.Semantic proximity Read ↗

An mRNA structure that controls gene expression by binding S-adenosylmethionine.Semantic proximity Read ↗

Cobalamin riboswitches exhibit a broad range of ability to discriminate between methylcobalamin and adenosylcobalamin.Semantic proximity Read ↗

An adenosyl-cobalamin (coenzyme-B12)-repressed translational enhancer in the cob mRNA of Salmonella typhimurium.Semantic proximity Read ↗

Conformational Change of a Tryptophan Residue in BtuF Facilitates Binding and Transport of Cobinamide by the Vitamin B12 Transporter BtuCD-F.Semantic proximity Read ↗

Cobalamin (vitamin B12) repression of the Cob operon in Salmonella typhimurium requires sequences within the leader and the first translated open reading frame.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.