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Article

Hepatitis C virus whole genome position weight matrix and robust primer design.

BMC microbiology - 25 Sept 2002

Qiu Ping, Cai Xiao-Yan, Wang Luquan, Greene Jonathan R, Malcolm Bruce

Abstract excerpt

BACKGROUND: The high degree of sequence heterogeneity found in Hepatitis C virus (HCV) isolates, makes robust nucleic acid-based assays difficult to generate. Polymerase chain reaction based techniques, require efficient and specific sequence recognition. Generation of robust primers capable of recognizing a wide range of isolates is a difficult task. RESULTS: A position weight matrix (PWM) and a consensus...

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Identifiers

PMID: 12323075
DOI: 10.1186/1471-2180-2-29
PMCID: PMC130017

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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