Article
The Glu298Asp polymorphism in endothelial nitric oxide synthase gene is associated with coronary in-stent restenosis.
International journal of cardiology - 1 Nov 2002
Suzuki Tomomichi, Okumura Kenji, Sone Takahito, Kosokabe Tai, Tsuboi Hideyuki, Kondo Junichiro, Mukawa Hiroaki, Kamiya Hiroki, Tomida Takahito, Imai Hajime, Matsui Hideo, Hayakawa Tetsuo
Abstract excerpt
BACKGROUND: Reduced or impaired synthesis of nitric oxide promotes the proliferation of vascular smooth muscle cells, and thus may induce the neointimal formation leading to coronary in-stent restenosis. Recent reports have suggested that the Glu298Asp polymorphism in exon 7 of the endothelial nitric oxide synthase gene is associated with coronary spasm and acute myocardial infarction. In this study, we have...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
