Article
Endothelial nitric oxide synthase gene polymorphism and acute myocardial infarction.
Hypertension (Dallas, Tex. : 1979) - 1 Sept 1998
Hibi K, Ishigami T, Tamura K, Mizushima S, Nyui N, Fujita T, Ochiai H, Kosuge M, Watanabe Y, Yoshii Y, Kihara M, Kimura K, Ishii M, Umemura S
Abstract excerpt
Recently a point mutation of guanine to thymine at nucleotide position 1917 in the endothelial nitric oxide synthase (eNOS) gene has been reported to be associated with coronary artery spasm. In addition, a significant association of the 4a/b polymorphism in intron 4 of the eNOS gene with coronar...
Topics
- Case-Control Studies
- Coronary Angiography
- Coronary Artery Disease
- Female
- Genotype
- Humans
- Japan
- Male
- Middle Aged
- Myocardial Infarction
- Nitric Oxide
- Nitric Oxide Synthase
- Nitric Oxide Synthase Type III
- Point Mutation
- Polymorphism, Genetic