Article
Gene dosage and linezolid resistance in Enterococcus faecium and Enterococcus faecalis.
Antimicrobial agents and chemotherapy - 1 Oct 2002
Marshall S H, Donskey C J, Hutton-Thomas R, Salata R A, Rice L B
Abstract excerpt
Resistance to linezolid has been associated with a G2576U mutation in domain V of the 23S rRNA. We analyzed nine clinical isolates of linezolid-resistant enterococci and showed a clear association between the number of 23S rRNA genes containing this mutation and the level of linezolid resistance...
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