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Article

Dopamine up-regulates Th17 phenotype from individuals with generalized anxiety disorder.

Journal of neuroimmunology - 15 Sept 2011

Ferreira Thais B, Kasahara Taissa M, Barros Priscila O, Vieira Morgana M M, Bittencourt Vera Carolina B, Hygino Joana, Andrade Regis M, Linhares Ulisses C, Andrade Arnaldo F, Bento Cleonice A

Abstract excerpt

Our objective was to evaluate the effect of stress-related dose of dopamine (DA) on the in vitro proliferation and cytokine production in polyclonally-activated T cells from healthy individuals or individuals with generalized anxiety disorder (GAD). Our results demonstrated that cell cultures from GAD group proliferated less following T cell activation, as compared with control group. The addition of DA reduced...

Topics

Adolescent
Adult
Antigens, CD
Anxiety Disorders
Cell Proliferation
Cell Survival
Cells, Cultured
Cytokines
Dopamine
Enzyme-Linked Immunosorbent Assay

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Female

Flow Cytometry

Glucocorticoids

Humans

Male

Mitogens

Phenotype

Phytohemagglutinins

Source

Identifiers

PMID: 21872345
DOI: 10.1016/j.jneuroim.2011.06.009

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