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Article

Bcl-6 p53 mutations in lymphomas carrying the bcl-2/Jh rearrangement.

Haematologica - 1 Sept 2002

Bellido Mar, Capello Daniela, Altés Albert, Estivill Camino, Gaidano Gianluca, Pujol Ramón, Bordes Ramón, Baiget Montserrat, Saglio Giuseppe, Sierra Jorge, Nomdedéu Josep F

Abstract excerpt

BACKGROUND AND OBJECTIVES: The t(14;18)(q32;q21) chromosomal translocation is the hallmark of follicular lymphomas (FL). The translocation induces the overexpression of the Bcl-2 protein and prolongs the survival of clonogenic cells. Tumor cells may acquire additional molecular alterations that may be associated with histologic progression or with chemo-resistance. DESIGN AND METHODS: We analyzed the distribution...

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Share to Chromosomes, Human, Pair 14
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, bcl-2

Share to Lymphoma, Follicular

Share to Proto-Oncogene Proteins c-bcl-2

Share to Proto-Oncogene Proteins c-bcl-6

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Share to Translocation, Genetic

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PMID: 12217802

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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