Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Enhancement of osteogenesis on hydroxyapatite surface coated with synthetic peptide (EEEEEEEPRGDT) in vitro.

Journal of biomedical materials research - 1 Nov 2002

Itoh D, Yoneda S, Kuroda S, Kondo H, Umezawa A, Ohya K, Ohyama T, Kasugai S

Abstract excerpt

Some dental implants are coated with hydroxyapatite (HA), which preferentially binds to bone. Several matrix proteins have an arginine-glycine-aspartic acid (RGD) sequence where cells attach via an integrin receptor. We hypothesized that coating an HA surface with an RGD-containing peptide might enhance the attachment and differentiation of osteoblasts. The HA disks (diameter 34 mm, thickness 1 mm) were treated...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biocompatible Materials
Share to Calcification, Physiologic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Adhesion

Share to Durapatite

Share to Oligopeptides

Share to Osteogenesis

Share to Peptides

Share to Stimulation, Chemical

Source

Identifiers

PMID: 12209950
DOI: 10.1002/jbm.10338

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Enhancement of osteogenesis on hydroxyapatite surface coated with synthetic peptide (EEEEEEEPRGDT) in vitro.PMID 12209950Read ↗

Differentiation of human bone-derived cells grown on GRGDSP-peptide bound titanium surfaces.Semantic proximity Read ↗

RGD peptides immobilized on a mechanically deformable surface promote osteoblast differentiation.Semantic proximity Read ↗

Effect of micro-nano-hybrid structured hydroxyapatite bioceramics on osteogenic and cementogenic differentiation of human periodontal ligament stem cell via Wnt signaling pathway.Semantic proximity Read ↗

Hydroxyapatite accelerates differentiation and suppresses growth of MC3T3-E1 osteoblasts.Semantic proximity Read ↗

Antimicrobial and osteogenic properties of a hydrophilic-modified nanoscale hydroxyapatite coating on titanium.Semantic proximity Read ↗

Phenotype and gene expression pattern of osteoblast-like cells cultured on polystyrene and hydroxyapatite with pre-adsorbed type-I collagen.Semantic proximity Read ↗

Promotion of pro-osteogenic responses by a bioactive ceramic coating.Semantic proximity Read ↗

Chemical modification of an implant surface increases osteogenesis and simultaneously reduces osteoclastogenesis: an in vitro study.Semantic proximity Read ↗

Effect of hydroxyapatite-based biomaterials on human osteoblast phenotype.Semantic proximity Read ↗

Effect of hydroxyapatite microspheres, amoxicillin-hydroxyapatite and collagen-hydroxyapatite composites on human dental pulp-derived mesenchymal stem cellsSemantic proximity Read ↗

Apatite content of collagen materials dose-dependently increases pre-osteoblastic cell deposition of a cement line-like matrix.Semantic proximity Read ↗

Accelerated Nucleation of Hydroxyapatite Using an Engineered Hydrophobin Fusion Protein.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.