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Article

Chemical modification of an implant surface increases osteogenesis and simultaneously reduces osteoclastogenesis: an in vitro study.

Clinical oral implants research - 1 Jun 2011

Mamalis Anastasios A, Markopoulou Cleopatra, Vrotsos Ioannis, Koutsilirieris Michael

Abstract excerpt

OBJECTIVES: The present study investigated the effect of a chemical modification of the SLA surface (SLActive surface) on human periodontal ligament (hPDL) cell (1) adhesion, (2) proliferation, (3) osteogenic differentiation (core binding factor α-1 [Cbfa-1], bone morphogenetic protein-7 [BMP-7] gene expression and alkaline phosphatase [ALP] activity) and (4) osteoclast formation and activity (osteoprotegerin...

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Source

Identifiers

PMID: 21070383
DOI: 10.1111/j.1600-0501.2010.02027.x

Genes

SLA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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