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Article

Accelerated Nucleation of Hydroxyapatite Using an Engineered Hydrophobin Fusion Protein.

Biomacromolecules - 9 May 2016

Melcher Melanie, Facey Sandra J, Henkes Thorsten M, Subkowski Thomas, Hauer Bernhard

Abstract excerpt

Calcium phosphate mineralization is of particular interest in dental repair. A biomimetic approach using proteins or peptides is a highly promising way to reconstruct eroded teeth. In this study, the screening of several proteins is described for their binding and nucleating activities toward hydroxyapatite. Out of 27 tested candidates, only two hydrophobin fusion proteins showed binding abilities to...

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PMID: 27010648
DOI: 10.1021/acs.biomac.6b00135

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