Article
The art and design of genetic screens: filamentous fungi.
Nature reviews. Genetics - 1 Sept 2002
Casselton Lorna, Zolan Miriam
Abstract excerpt
In the 1940s, screens for metabolic mutants of the filamentous fungus Neurospora crassa established the fundamental, one-to-one relationship between a gene and a specific protein, and also established fungi as important genetic organisms. Today, a wide range of filamentous species, which represents a billion years of evolutionary divergence, is used for experimental studies. The developmental complexity of these...
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