Article
The population genetics of adaptation: the adaptation of DNA sequences.
Evolution; international journal of organic evolution - 1 Jul 2002
Orr H Allen
Abstract excerpt
I describe several patterns characterizing the genetics of adaptation at the DNA level. Following Gillespie (1983, 1984, 1991), I consider a population presently fixed for the ith best allele at a locus and study the sequential substitution of favorable mutations that results in fixation of the fittest DNA sequence locally available. Given a wild type sequence that is less than optimal, I derive the fitness rank...
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