Article
A general extreme value theory model for the adaptation of DNA sequences under strong selection and weak mutation.
Genetics - 1 Nov 2008
Joyce Paul, Rokyta Darin R, Beisel Craig J, Orr H Allen
Abstract excerpt
Recent theoretical studies of the adaptation of DNA sequences assume that the distribution of fitness effects among new beneficial mutations is exponential. This has been justified by using extreme value theory and, in particular, by assuming that the distribution of fitnesses belongs to the Gumbel domain of attraction. However, extreme value theory shows that two other domains of attraction are also possible:...
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