Article
Genetics, cytokines and human infectious disease: lessons from weakly pathogenic mycobacteria and salmonellae.
Nature genetics - 1 Sept 2002
Ottenhoff Tom H M, Verreck Frank A W, Lichtenauer-Kaligis Elgin G R, Hoeve Marieke A, Sanal Ozden, van Dissel Jaap T
Abstract excerpt
Host genetic factors are important in determining the outcome of infections caused by intracellular pathogens, including mycobacteria and salmonellae, but until now have been poorly characterized. Recently, some individuals with severe infections due to otherwise weakly pathogenic mycobacteria (non-tuberculous mycobacteria or Mycobacterium bovis bacille Calmette-Guérin) or Salmonella species have been shown to be...
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