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Article

Functional promoter polymorphism in SREBP cleavage-activating protein (SCAP).

Journal of human genetics - 1 Jan 2002

Cao Henian, Miskie Brooke A, Hegele Robert A

Abstract excerpt

We report the identification of a loss-of-function -11C>T promoter mutation in the gene encoding the sterol regulatory element binding protein cleavage-activating protein (SCAP). The -11T allele was associated with a marked reduction in promoter activity in a luciferase-based expression system. We also report additional common single-nucleotide polymorphisms in the SCAP promoter and coding sequence that were...

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Source

Identifiers

PMID: 12202990
DOI: 10.1007/s100380200072

Genes

SCAP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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Functional promoter polymorphism in SREBP cleavage-activating protein (SCAP).PMID 12202990Read ↗

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