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Article

The modulation of mitochondrial nitric-oxide synthase activity in rat brain development.

The Journal of biological chemistry - 8 Nov 2002

Riobo Natalia A, Melani Mariana, Sanjuan Norberto, Fiszman Monica L, Gravielle Maria Clara, Carreras M Cecilia, Cadenas Enrique, Poderoso Juan J

Abstract excerpt

Different mitochondrial nitric-oxide synthase (mtNOS) isoforms have been described in rat and mouse tissues, such as liver, thymus, skeletal muscle, and more recently, heart and brain. The modulation of these variants by thyroid status, hypoxia, or gene deficiency opens a broad spectrum of mtNOS-dependent tissue-specific functions. In this study, a new NOS variant is described in rat brain with an M(r) of 144 kDa...

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Identifiers

PMID: 12202479
DOI: 10.1074/jbc.M204580200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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