Telomere formation on macronuclear chromosomes of Oxytricha trifallax and O. fallax: alternatively processed regions have multiple telomere addition sites.

doi:10.1186/1471-2156-3-16

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Article

Telomere formation on macronuclear chromosomes of Oxytricha trifallax and O. fallax: alternatively processed regions have multiple telomere addition sites.

BMC genetics - 28 Aug 2002

Williams Kevin R, Doak Thomas G, Herrick Glenn

Abstract excerpt

BACKGROUND: Ciliates employ massive chromatid breakage and de novo telomere formation during generation of the somatic macronucleus. Positions flanking the 81-MAC locus are reproducibly cut. But those flanking the Common Region are proposed to often escape cutting, generating three nested macronuclear chromosomes, two retaining "arms" still appended to the Common Region. Arm-distal positions must differ (in cis)...

Topics

Alleles
Animals
Base Sequence
Cell Nucleus
Chromatids
Chromosome Breakage
Chromosome Mapping
Clone Cells
Models, Genetic
Molecular Sequence Data
Oxytricha
Polymerase Chain Reaction
Telomere

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Identifiers

PMID: 12199911
DOI: 10.1186/1471-2156-3-16
PMCID: PMC128808

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