Article
DNA rearrangements directed by non-coding RNAs in ciliates.
Wiley interdisciplinary reviews. RNA - 1 Jan 2000
Mochizuki Kazufumi
Abstract excerpt
Extensive programmed rearrangement of DNA, including DNA elimination, chromosome fragmentation, and DNA unscrambling, takes place in the newly developed macronucleus during the sexual reproduction of ciliated protozoa. Recent studies have revealed that two distant classes of ciliates use distinct types of non-coding RNAs to regulate such DNA rearrangement events. DNA elimination in Tetrahymena is regulated by...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
