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Article

Studying MHC class II transport in dendritic cells.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2013

Paul Petra, Neefjes Jacques

Abstract excerpt

Professional antigen presenting cells, such as dendritic cells, are effective in activating T lymphocytes due to their unique ability to present antigens in the context of both MHC class I and II molecules. After successful loading with antigenic peptides MHC class II molecules traffic from the late endosomal loading compartment to the plasma membrane to exert their function of presenting peptides to T helper...

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PMID: 23329509
DOI: 10.1007/978-1-62703-218-6_36

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