Article
Association of symptomatic acute human parvovirus B19 infection with human leukocyte antigen class I and II alleles.
The Journal of infectious diseases - 15 Aug 2002
Kerr Jonathan R, Mattey Derek L, Thomson Wendy, Poulton Kay V, Ollier William E R
Abstract excerpt
To determine the effect of the major histocompatibility complex on the development of symptoms during acute human parvovirus B19 infection, we compared human leukocyte antigen (HLA) class I and II alleles in 36 patients with symptomatic acute B19 infection with those in >900 control subjects from northwestern England. The frequency of each of HLA-DRB1*01 (P=.016), DRB1*04 (P=.007), and DRB1*07 (P<.0001) alleles...
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