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Sustained CD8 + T-Cell Responses Induced after Acute Parvovirus B19 Infection in Humans

1 Sept 2005

Abstract excerpt

Murine models have suggested that CD8+ T-cell responses peak early in acute viral infections and are not sustained, but no evidence for humans has been available. To address this, we longitudinally analyzed the CD8+ T-cell response to human parvovirus B19 in acutely infected individuals. We observed striking CD8+ T-cell responses, which were sustained or even increased over many months after the resolution of...

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PMID: 16140790
DOI: 10.1128/jvi.79.18.12117-12121.2005

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