Article
[Function of the CLC chloride channels and their implication in human pathology].
Nephrologie - 1 Jan 2002
Vandewalle A
Abstract excerpt
To date, nine chloride channels belonging to the family of CLC chloride channels have been identified. They are localized either in plasma membranes or in intracellular vesicles (endosomes or lysosomes) and can have an ubiquitus or a more restrained tissue distribution. Recent studies on ClC-K1, ClC-2, ClC-3, ClC-5 and ClC-7 knockout mice and the identification of human inherited diseases caused by mutations of...
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