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Article

Papillary Thyroid Carcinoma in Patients with RET Proto-Oncogene Germline Mutation

1 Jul 2002

Abstract excerpt

The occurrence of papillary thyroid carcinoma in patients with RET germline mutations has been described in only eight cases since 1993. We report three women with a RET germline mutation in exon 13 and 14, affecting codon 790, 791, and 804, respectively, who underwent prophylactic thyroidectomy at the age of 29, 39, and 24 years, respectively. Histologic examination revealed C-cell hyperplasia and a small...

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PMID: 12193298
DOI: 10.1089/105072502320288393

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