Article
Large-scale mutagenesis and functional genomics in yeast.
Functional & integrative genomics - 1 Sept 2002
Que Qiang Q, Winzeler Elizabeth A
Abstract excerpt
One of the major goals for the post-genome era is determining of the function of proteins predicted in the genome sequence. In many organisms functional assignments have been the results of comparative sequencing, proteomics or expression profiling. In the yeast, Saccharomyces cerevisiae, however, the functional role of a gene can be tested directly by disrupting the gene and examining the phenotype of the...
Topics
- Genes, Lethal
- Genome, Fungal
- Genomics
- Mutagenesis
- Phenotype
- Saccharomyces cerevisiae