Article
Role of ICAM-1 and E-selectin gene polymorphisms in pathogenesis of PAOD in Egyptian patients.
Vascular health and risk management - 4 Feb 2010
Shaker Olfat, Zahra Amr, Sayed Ahmed, Refaat Ayman, El-Khaiat Zakaria, Hegazy Gehan, El-Hindawi Khaled, Ay-El Deen Mohamed
Abstract excerpt
BACKGROUND: Intercellular adhesion molecule-1 (ICAM-1) and E-selectin have been shown to predict cardiovascular disease (CVD) such as myocardial infarction, stroke, and peripheral arterial occlusive disease (PAOD). METHODS: Two mutations, S128R in E-selectin and K469E in ICAM-1, were investigated in 156 patients with PAOD and 100 control subjects using polymerase chain reaction-restriction fragment length...
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