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Article

Motifs within the CLN3 protein: modulation of cell growth rates and apoptosis.

Human molecular genetics - 1 Sept 2002

Persaud-Sawin Dixie-Ann N W, VanDongen Antonius, Boustany Rose-Mary N

Abstract excerpt

Juvenile Batten disease (JNCL) is an autosomal recessive disease that results from mutations in the CLN3 gene. The wild-type CLN3 gene coding sequence has 15 exons, and the translated protein consists of 438 amino acids. The most commonly observed mutation is a 1.02 kb deletion in the genomic DNA. This deletion results in a truncated protein due to the loss of amino acids 154-438, and the introduction of 28 novel...

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Source

Identifiers

PMID: 12189165
DOI: 10.1093/hmg/11.18.2129

Genes

CLN3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Motifs within the CLN3 protein: modulation of cell growth rates and apoptosis.PMID 12189165Read ↗

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