Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mutation analysis of the BRCA1 gene in Malaysian breast cancer patients.

Singapore medical journal - 1 Apr 2002

Balraj P, Khoo A S B, Volpi L, Tan J A M A, Nair S, Abdullah H

Abstract excerpt

Thirty patients with early onset breast cancer or familial breast cancer from Malaysia were analysed for germline mutation in the early onset breast cancer I gene (BRCA1). Direct sequencing of the entire coding region of BRCA1 identified a frameshift mutation, c.5447-5448insC (insC5447) (codon 1776 of exon 21) in a patient aged 32 of the Malay ethnic origin, who had no family history of breast and/or ovarian...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Breast Neoplasms
Share to BRCA1 gene

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, BRCA1

Share to Genetic Testing

Share to Malaysia

Share to Mutation

Share to Polymorphism, Genetic

Source

Identifiers

PMID: 12188064

Genes

BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mutation analysis of the BRCA1 gene in Malaysian breast cancer patients.PMID 12188064Read ↗

BRCA1 and BRCA2 Germline Mutations in Malaysian Women with Early-Onset Breast Cancer without a Family HistorySemantic proximity Read ↗

BRCA1 c.2845insA is a founder mutation in Singaporean Malay women with early onset breast/ovarian cancer.Semantic proximity Read ↗

Characterization of BRCA1 and BRCA2 variants in multi-ethnic Asian cohort from a Malaysian case-control study.Semantic proximity Read ↗

Founder mutation in the BRCA1 gene in Malay breast cancer patients from Singapore.Semantic proximity Read ↗

Identification of Mutation in Exon11 of BRCA1 Gene in Bangladeshi Patients with Breast Cancer.Semantic proximity Read ↗

BRCA1 c.2845insA is a recurring mutation with a founder effect in Singapore Malay women with early onset breast/ovarian cancer.Semantic proximity Read ↗

Investigation of BRCA1 exon 11 genetic variations in breast cancer among Libyan womenSemantic proximity Read ↗

BRCA1 Exon 11 Mutations in Breast Cancer: A Study From Pakistan.Semantic proximity Read ↗

BRCA1 disease-associated haplotypes in Singapore Malay women with early-onset breast/ovarian cancer.Semantic proximity Read ↗

Evaluation of BRCA1 and BRCA2 mutations and risk-prediction models in a typical Asian country (Malaysia) with a relatively low incidence of breast cancer.Semantic proximity Read ↗

Novel germline BRCA1 mutations detected in women in singapore who developed breast carcinoma before the age of 36 years.Semantic proximity Read ↗

A novel frequent BRCA1 allele in Chinese patients with breast cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.