Article
Novel germline BRCA1 mutations detected in women in singapore who developed breast carcinoma before the age of 36 years.
Cancer - 15 Aug 2000
Ho G H, Phang B H, Ng I S, Law H Y, Soo K C, Ng E H
Abstract excerpt
BACKGROUND: In recent years, although BRCA1 has been extensively investigated, the contribution of inherited BRCA1 mutations to breast carcinoma in Asian populations is largely unknown. The authors undertook this study to determine the prevalence and spectrum of germline BRCA1 mutations among women in Singapore with early onset breast carcinoma. METHODS: Forty-three of 72 eligible patients whose breast carcinoma...
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