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Article

Interferon regulatory factor 3 is a cellular partner of rotavirus NSP1.

Journal of virology - 1 Sept 2002

Graff Joel W, Mitzel Dana N, Weisend Carla M, Flenniken Michelle L, Hardy Michele E

Abstract excerpt

The rotavirus nonstructural protein NSP1 is the least conserved protein in the rotavirus genome, and its function in the replication cycle is not known. We employed NSP1 as bait in the yeast two-hybrid interaction trap to identify candidate cellular partners of NSP1 that may provide clues to its function. Interferon regulatory factor 3 (IRF-3) was identified as an NSP1 interactor. NSP1 synthesized in...

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Source

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Identifiers

PMID: 12186937
DOI: 10.1128/jvi.76.18.9545-9550.2002
PMCID: PMC136439

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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