Article
Identification and characterization of two novel bla(KLUC) resistance genes through large-scale resistance plasmids sequencing.
PloS one - 1 Jan 2012
Xu Teng, Ying Jun, Yao Xiaoding, Song Yulong, Ma Ping, Bao Bokan, Jiang Weiyan, Wu Xinmei, Tou Huifen, Li Peizhen, Ren Ping, Fei Jingxian, Yang Lei, Liu Qi, Xu Zuyuan, Zhou Tieli, Ni Liyan, Bao Qiyu
Abstract excerpt
Plasmids are important antibiotic resistance determinant carriers that can disseminate various drug resistance genes among species or genera. By using a high throughput sequencing approach, two groups of plasmids of Escherichia coli (named E1 and E2, each consisting of 160 clinical E. coli strains isolated from different periods of time) were sequenced and analyzed. A total of 20 million reads were obtained and...
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