Article
The role of common gamma chain in human monocytes in vivo; evaluation from the studies of X-linked severe combined immunodeficiency (X-SCID) carriers and X-SCID patients who underwent cord blood stem cell transplantation.
British journal of haematology - 1 Sept 2002
Ariga Tadashi, Yamaguchi Koji, Yoshida Jukei, Miyanoshita Akihiko, Watanabe Toshihide, Date Tadashi, Miura June-Ichi, Kumaki Satoru, Ishii Naoto, Sakiyama Yukio
Abstract excerpt
Expression of common gamma chain (gammac) on monocytes was studied in five carriers of X-linked severe combined immunodeficiency (X-SCID) and two X-SCID patients who underwent cord blood stem cell transplantation (CBSCT). Flow cytometric analysis revealed that both gammac-negative and positive monocytes co-existed in X-SCID carriers, whereas no gammac-negative T, B or NK cells were observed in them. Clonal...
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