Article
Significance of genetic information in risk assessment and individual classification using silicosis as a case model.
The Annals of occupational hygiene - 1 Jun 2002
McCanlies Erin, Landsittel Douglas P, Yucesoy Berran, Vallyathan Val, Luster Michael L, Sharp Dan S
Abstract excerpt
Over the last decade the role of genetic data in epidemiological research has expanded considerably. We recently published a case-control study that evaluated the interaction between silica exposure and minor variants in the genes coding for interleukin-1alpha (IL-1alpha), interleukin-1 receptor antagonist (IL-1RA) and tumor necrosis factor alpha (TNFalpha) as risk factors associated with silicosis, a fibrotic...
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