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Article

Independent origin of 185delAG BRCA1 mutation in an Indian family.

Neoplasma - 1 Jan 2007

Kadalmani K, Deepa S, Bagavathi S, Anishetty Sharmila, Thangaraj K, Gajalakshmi P

Abstract excerpt

BRCA1 and BRCA2 are the two major breast cancer susceptibility genes. We tested members of a family with multiple cases of breast cancer, for mutations in the BRCA1 gene. Analysis of the PCR amplicons of all the exons (22) of the BRCA1 gene using conformation sensitive gel electrophoresis (CSGE) revealed a heteroduplex band pattern in exon 2 of the proband (III-3) in this family. The amplicon was further...

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Source

Identifiers

PMID: 17203892

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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