Article
Menin's interaction with glial fibrillary acidic protein and vimentin suggests a role for the intermediate filament network in regulating menin activity.
Experimental cell research - 15 Aug 2002
Lopez-Egido Juan, Cunningham Janet, Berg Mikael, Oberg Kjell, Bongcam-Rudloff Erik, Gobl Anders
Abstract excerpt
Recently the multiple endocrine neoplasia type 1 (MEN1) tumor suppressor gene was cloned. Its protein product, called menin, has been shown to associate with the AP1 transcription factor JunD and to repress JunD-mediated transcription. However, little is known concerning the regulation of menin. Here we report that menin interacts with the type III intermediate filament (IF) proteins glial fibrillary acidic...
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