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Article

Menin represses JunD-activated transcription by a histone deacetylase-dependent mechanism.

Biochimica et biophysica acta - 6 Oct 1999

Gobl A E, Berg M, Lopez-Egido J R, Oberg K, Skogseid B, Westin G

Abstract excerpt

Recently the multiple endocrine neoplasia type 1 (MEN-1) tumor suppressor gene was cloned. MEN-1 encodes a nuclear protein, called menin, of hitherto unknown function. In order to investigate the biological function of menin we employed the yeast two-hybrid system to identify menin-interacting proteins. Here we report that menin functions as a transcriptional repressor through interaction with the transcription...

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Identifiers

PMID: 10500243
DOI: 10.1016/s0167-4781(99)00132-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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