Article
Transgenic mouse models of neurodegenerative disease: opportunities for therapeutic development.
Current neurology and neuroscience reports - 1 Sept 2002
Jankowsky Joanna L, Savonenko Alena, Schilling Gabriele, Wang Jiou, Xu Guilian, Borchelt David R
Abstract excerpt
Neurodegenerative diseases present an extraordinary challenge for medicine due to the grave nature of these illnesses, their prevalence, and their impact on individuals and caregivers. The most common of these age-associated chronic illnesses are Alzheimer's disease (AD) and Parkinson's disease (PD); other examples include the prion disorders, amyotrophic lateral sclerosis (ALS), and the trinucleotide (CAG)...
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