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Article

SOX8 acts as a prognostic factor and mediator to regulate the progression of triple-negative breast cancer

24 Feb 2019

Abstract excerpt

The molecular mechanisms underlying triple-negative breast cancer (TNBC) pathology are not fully understood. Here, we reviewed the SOX8 transcript level in 24 types of cancer and normal tissues and the SOX8 expression pattern in breast cancer from the TCGA and METABRIC data sets and found that SOX8 was highly expressed in TNBC. We investigated the effect of SOX8 on tumorigenicity, migration and apoptosis in TNBC...

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PMID: 30810729
DOI: 10.1093/carcin/bgz034

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