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Article

Expression of human SOX7 in normal tissues and tumors

1 Apr 2002

Abstract excerpt

SOX transcription factors with high-mobility-group DNA-binding domain (HMG box) play key roles in embryogenesis. Some members of the SOX family are negative regulators of the WNT-beta-catenin-TCF signaling pathway. We have previously cloned and characterized human SOX17, constituting a subfamily with SOX7 and SOX18. Another group mapped SOX7 gene to human chromosome 8p22, and reported almost ubiquitous expression...

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Identifiers

PMID: 11891528
DOI: 10.3892/ijmm.9.4.363

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