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Article

Clostridium botulinum C2 toxin: binding studies with fluorescence-activated cytometry.

Toxicon : official journal of the International Society on Toxinology - 1 Aug 2002

Stiles Bradley G, Blöcker Dagmar, Hale Martha L, Guetthoff Mary Ann, Barth Holger

Abstract excerpt

Clostridium botulinum C2 enterotoxin consists of two unlinked proteins designated as C2II, which recognizes a cell-surface glycoprotein and translocates an ADP-ribosyltransferase, C2I, into the cytosol of a targeted cell. Fluorescence-activated cytometry was used to study the cellular interactions of Alexa488-labeled C2I (C2I-A488) and proteolytically activated C2II (C2IIa-A488). The binding of C2IIa-A488 (4...

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PMID: 12165316
DOI: 10.1016/s0041-0101(02)00113-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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