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Article

HPV16/18 prevalence in cervical lesions/cancers and p53 genotypes in cervical cancer patients from India.

Gynecologic oncology - 1 Aug 2002

Saranath D, Khan Z, Tandle A T, Dedhia P, Sharma B, Contractor R, Shrivastava S, Dinshaw K

Abstract excerpt

OBJECTIVES: The HPV16/18 code for an oncoprotein-E6, which binds to p53 tumor suppressor protein and degrades the protein via ubiquitination. A common polymorphism of p53 in exon 4 codon 72, resulting in either proline (Pro) or arginine (Arg), affects HPV16/18 E6-mediated degradation of p53 protein in vivo. Hence, in the current study we investigated the prevalence of HPV16/18 in cervical lesions and the...

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Identifiers

PMID: 12144822
DOI: 10.1006/gyno.2002.6735

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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