Article
Essential function of Wnt-4 for tubulogenesis in the Xenopus pronephric kidney.
Developmental biology - 1 Aug 2002
Saulnier Didier M E, Ghanbari Hedyeh, Brändli André W
Abstract excerpt
In the vertebrate embryo, development of the excretory system is characterized by the successive formation of three distinct kidneys: the pronephros, mesonephros, and metanephros. While tubulogenesis in the metanephric kidney is critically dependent on the signaling molecule Wnt-4, it is unknown whether Wnt signaling is equally required for the formation of renal epithelia in the other embryonic kidney forms. We...
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