Article
Requirement of Wnt/beta-catenin signaling in pronephric kidney development.
Mechanisms of development - 1 Jan 2000
Lyons Jon P, Miller Rachel K, Zhou Xiaolan, Weidinger Gilbert, Deroo Tom, Denayer Tinneke, Park Jae-Il, Ji Hong, Hong Ji Yeon, Li Annette, Moon Randall T, Jones Elizabeth A, Vleminckx Kris, Vize Peter D, McCrea Pierre D
Abstract excerpt
The pronephric kidney controls water and electrolyte balance during early fish and amphibian embryogenesis. Many Wnt signaling components have been implicated in kidney development. Specifically, in Xenopus pronephric development as well as the murine metanephroi, the secreted glycoprotein Wnt-4 has been shown to be essential for renal tubule formation. Despite the importance of Wnt signals in kidney...
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