Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Simultaneous genotyping of single nucleotide polymorphisms in the IL-6, IL-10, TNFalpha and TNFbeta genes.

Tissue antigens - 1 Apr 2002

Tseng L-H, Chen P-J, Lin M-T, Singleton K, Martin E G, Yen A-H, Chuang S-M, Martin P J, Hansen J A

Abstract excerpt

Single nucleotide polymorphisms (SNP) in the human IL-6, IL-10, TNFalpha and TNFbeta genes have been associated with gene function and susceptibility to disease. In this study, primers containing mismatches at 1-3 nucleotide positions were designed to incorporate a new restriction site recognized by endonucleases AlwNI, BcgI, BglI, BsaBI, BslI, BstXI, EcoNI or XcmI for genotyping SNPs in the IL-6 gene (position -...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytokines
Share to DNA Primers
Share to Interleukin-10

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Interleukin-6

Share to Lymphotoxin-alpha

Share to Polymerase Chain Reaction

Share to Polymorphism, Restriction Fragment Length

Share to Tumor Necrosis Factor-alpha

Source

Identifiers

PMID: 12135426
DOI: 10.1034/j.1399-0039.2002.590405.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Simultaneous genotyping of single nucleotide polymorphisms in the IL-6, IL-10, TNFalpha and TNFbeta genes.PMID 12135426Read ↗

Association of IL-6, TNF-α and IL-10 gene polymorphisms with type 2 diabetes mellitus.Semantic proximity Read ↗

ARMS-PCR methodologies to determine IL-10, TNF-α, TNF-β and TGF-β1 gene polymorphismsSemantic proximity Read ↗

Distribution of the IL-1RN, IL-6, IL-10, INF-γ, and TNF-α Gene Polymorphisms in the Mexican Population.Semantic proximity Read ↗

Analyses of functional IL10 and TNF-α genotypes in Behçet's syndrome.Semantic proximity Read ↗

Simultaneous analysis of interleukin-10 gene microsatellites and single-nucleotide polymorphisms in parallel with tumour necrosis factor and interferon-gamma short tandem repeats by fluorescence-based polymerase chain reaction.Semantic proximity Read ↗

A comparison of methods for determining genotypes at the tumour necrosis factor-alpha-308, interleukin (IL)-1beta+3953, IL-6 -174 and IL-10 -1082/-819/-592 polymorphic loci.Semantic proximity Read ↗

Genotyping of single nucleotide polymorphisms in cytokine genes using real-time PCR allelic discrimination technology.Semantic proximity Read ↗

Simultaneous genotyping of single nucleotide polymorphisms in the IL-1 gene complex by multiplex polymerase chain reaction-restriction fragment length polymorphism.Semantic proximity Read ↗

Induced heteroduplex genotyping of TNF-alpha, IL-1beta, IL-6 and IL-10 polymorphisms associated with transcriptional regulation.Semantic proximity Read ↗

Identification and efficient genotyping of an (A)n/(T)m polymorphism within the 5' untranslated region of the human IL6 gene.Semantic proximity Read ↗

Interleukin-10 gene promoter polymorphism in English and Polish healthy controls. Polymerase chain reaction haplotyping using 3' mismatches in forward and reverse primers.Semantic proximity Read ↗

A novel PCR-RFLP assay for the detection of the single nucleotide polymorphism at position -1082 in the human IL-10 gene promoter.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.