Article
ICAM-1 Polymorphisms (G241R, K469E), in Coronary Artery Disease and Myocardial Infarction
Iranian journal of immunology : IJI - 1 Dec 2007
Aminian Bahram, Abdi Ardekani Ali Reza, Arandi Narges
Abstract excerpt
BACKGROUND: Inflammation plays a critical role in atherogenesis. The initial step in atherosclerosis is the adhesion of leukocytes to activated endothelial cells mediated by ICAM-1, an inflammatory protein. Several polymorphisms for Intracellular adhesion molecule -1(ICAM-) gene have been described. OBJECTIVES: To determine the possible role of G241R and K469E polymorphisms in development of coronary artery...
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