Article
Prevalence of mutations related to HIV-1 antiretroviral resistance in Brazilian patients failing HAART.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Jul 2002
Tanuri Amilcar, Caridea Elena, Dantas Maria C, Morgado Marisa G, Mello Daise L C, Borges Sandra, Tavares Marisa, Ferreira Selma B, Santoro-Lopes Guilherme, Martins Claudia R F, Esteves André L C, Diaz Ricardo S, Andreo Sandra M S, Ferreira Luiz A P, Rodrigues Rodrigo, Reuter Tania, Cavalcanti Ana M S, de Oliveira Suelene M, de Barbosa Heraclito B, Teixeira Paulo R, Chequer Pedro N
Abstract excerpt
BACKGROUND: Current guidelines for antiretroviral (ARV) therapy recommend at least triple-drug combination, the so-called highly active antiretroviral therapy (HAART). Not all patients respond to HAART and the development of drug resistance remains one of the most serious obstacles to sustained suppression of HIV. OBJECTIVE: In an attempt to correlate the HIV therapeutic failure with reverse transcriptase (RT)...
Topics
- Antiretroviral Therapy, Highly Active
- Brazil
- Cross-Sectional Studies
- Drug Resistance, Viral
- HIV Infections
- HIV Protease
- HIV Reverse Transcriptase
