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Article

Immunological markers predicting outcome in patients with hepatitis C treated with interferon-alpha and ribavirin.

Immunology and cell biology - 1 Aug 2002

Lee Silvia, Macquillan Gerry C, Keane Niamh M, Flexman James, Jeffrey Gary P, French Martyn Ah, Brochier Jean, Price Patricia

Abstract excerpt

Type 1 (T1) cytokine responses are required for the clearance of hepatitis C virus by cytotoxic T lymphocytes, but can promote liver damage. Interferon-alpha (IFN alpha) can be expected to promote T1 cytokine responses, so treatment outcome may depend on the T1/T2 cytokine environment and levels of immune activation at baseline. This model was tested by monitoring immunological markers in a pilot study of...

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PMID: 12121229
DOI: 10.1046/j.1440-1711.2002.01102.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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