Article
Phenotypes of a naturally defective recB allele in Neisseria meningitidis clinical isolates.
Infection and immunity - 1 Aug 2002
Salvatore Paola, Bucci Cecilia, Pagliarulo Caterina, Tredici Maurizio, Colicchio Roberta, Cantalupo Giuseppina, Bardaro Marcellino, Del Giudice Luigi, Massardo Domenica R, Lavitola Alfredo, Bruni Carmelo B, Alifano Pietro
Abstract excerpt
Neisseria meningitidis strains belonging to the hypervirulent lineage ET-37 and several unrelated strains are extremely UV sensitive. The phenotype is consequent to the presence of a nonfunctional recB(ET-37) allele carrying multiple missense mutations. Phenotypic analysis has been performed with congenic meningococcal strains harboring either the wild-type recB allele or the recB(ET-37) allele. Congenic...
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