Article
Possible association of a cholecystokinin promoter variant to schizophrenia.
American journal of medical genetics - 8 Jul 2002
Wang Zhewu, Wassink Thomas, Andreasen Nancy C, Crowe Raymond R
Abstract excerpt
Several lines of research indicate a cholecystokinin (CCK) deficit in schizophrenia patients. A C to T substitution was found in the promoter region of the CCK gene. We investigated this promoter variant in patients with schizophrenia and geographically-matchedcontrols. The T allele was detected in 24% of the 85 schizophrenics and 16% of the 247 controls. No significant difference in the T allele frequency was...
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