Localization of a gene for otosclerosis to chromosome 15q25-q26

Abstract excerpt

Among white adults otosclerosis is the single most common cause of hearing impairment. Although the genetics of this disease are controversial, the majority of studies indicate autosomal dominant inheritance with reduced penetrance. We studied a large multi-generational family in which otosclerosis has been inherited in an autosomal dominant pattern. Five of16 affected persons have surgically confirmed...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Ear Surgery and Otitis Media
• Share to Hearing, Cochlea, Tinnitus, Genetics
• Share to Vestibular and auditory disorders