Article
Genotyping of drug targets: a method to predict adverse drug reactions?
Drug safety - 1 Jan 2002
Güzey Cüneyt, Spigset Olav
Abstract excerpt
In the last decades, advances in molecular biology have led to modern pharmacogenetics, which started as a science that focused on investigating drug metabolising enzymes and genetic determinants of pharmacokinetic variability. As more evidence has become available on the structure of drug targets and the genes coding for them, increasing attention has been directed towards pharmacodynamic explanations of...
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